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Codeine operates by binding to opioid receptors in the brain, spinal cord, and other areas of the body, altering the perception of pain. This interaction modulates neurotransmitter release, ultimately leading to pain relief. Additionally, it can suppress coughing by affecting the brain's cough center.
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Precautions and Contraindications
Pregnancy and Lactation
Usage of Codeine during pregnancy or lactation necessitates cautious consideration due to potential risks to the fetus or newborn. Healthcare providers should evaluate the benefits against potential harm before prescribing.

Respiratory Conditions
Individuals with respiratory disorders, such as asthma or chronic obstructive pulmonary disease (COPD), should exercise caution when using Codeine due to its respiratory depressant effects.

Drug Interactions
Concomitant use of Codeine with certain medications, particularly other central nervous system depressants or monoamine oxidase inhibitors (MAOIs), can potentiate adverse effects and should be avoided or closely monitored.

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